New Study Reveals: No Sign of Melanoma After Treatment with This Pair of Drugs

A new study shows that a fifth of people with the most serious form of skin cancer had no sign of tumors in their body after treatment with a pair of immunotherapy drugs.

Drugs called ipilimumab and nivolumab can increase the survival rate of patients when used in combination. The study has shown that in 69% of patients in the trial on 142 patients.

Melanoma is one of the most serious forms of skin cancer and it kills more than 2,000 people in Britain every year. The results of the trial for these drugs were published in the Journal of the American Medical Association and it showed that one-third of the patients lived for one year without any signs of the tumor growing.

Immunity Against Infection

The immune system can help in a fight against infection, and there are many “breaks” that stop immunity to attack the tissue of our body. Cancer, on the other hand, can take advantage of those brakes, and these drugs are made to prevent cancer to do that.

This trial shows that a combination of these drugs helped patients, but more than half of them had severe to life-threatening side effects, so trial had to be stopped.

Dr. James Larkin, who ran part of the trial at the Royal Marsden Hospital in London, told the BBC News website: “It is very encouraging to see that survival rate.

“It will be important in terms of working out the benefit of these treatments in the longer term, but nevertheless, it’s a relatively small study still.”

Vicky Brown from Cardiff was diagnosed with malignant melanoma and it spread to her lungs and breast in April 2013. She started her therapy the same year.

“It worked within a month. There were lumps I could actually feel and they disappeared quite quickly,” she said.
She had some side effects such as upset liver and inflamed bowels, and after that cancer returned. She now has the second course of combination immunotherapy that might have shrunk the tumors. “My granddaughter is now coming up to four and I now have a second grandchild and not to have been part of their lives would have been heartbreaking, so I’m really thankful,” she added.

When some of the drugs and treatments fail, and cancer starts to grow again, then that means that drug becomes useless.

Dr. Larkin thinks, “we’re dealing with something different here”.

He added: “This combination of drugs alters the balance of the immune system, two years down the line the immune system might have stopped recognizing the tumor.”

“To me it is extremely encouraging that giving the combination again we can reintroduce recognition by the immune system – it is like a booster dose.”

Prof Richard Marais, from Cancer Research UK, said the results were “exciting” and “offer new hope to melanoma patients and their families”.

However, he added: “It’s important to remember that there’s an increased likelihood of severe side effects when these drugs are combined.

“We need to identify which patients are most likely to benefit from this combination and also which patients are most likely to experience the side effects.

“That will help doctors to ensure each patient gets the best treatment they need.”

Beating cancer without harsh treatments.

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They did so in an effort to protect their sponsors and to conceal the truth. Many of today’s largest industries are also the largest polluters and are therefore the greatest contributors to chronic disease and cancer.

These industries also happen to be the biggest financial donors to mainstream media outlets, which enables the vicious cycle of concealing the truth. But thanks to people like Bollinger, the truth about natural cancer cures can not be suppressed.

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